A-Pak

Aceclofenac is indicated for the relief of pain and inflammation in osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, toothache, trauma and lumbago.

<p>Aceclofenac is a non-steroidal drug with anti-inflammatory and analgesic properties. It is a potent inhibitor of the enzyme cyclooxygenase, which is involved in the production of prostaglandin. After oral administration, it is rapidly and completely absorbed an unchanged drug.</p>

<p><strong>Extended release tablet</strong>: The recommended dose in adults is one 200 mg Aceclofenac tablet daily or as prescribed by the physician.<br /><strong>Film coated tablet</strong>: The recommended dose in adults is 100 mg, twice daily.</p>

No significant drug interactions has not been observed but close monitoring of patients is required when it is used with:<br /> <ul> <li><strong>Lithium and Digoxin</strong>: may increase plasma concentration of lithium and digoxin.</li> <li><strong>Diuretics</strong>: may interact the activity of diuretics.</li> <li><strong>Anticoagulants</strong>: may enhance the activity of anticoagulant.</li> <li><strong>Methotrexate</strong>: may increase the plasma level of methotrexate.</li> </ul>

<p>Aceclofenac is contraindicated in patients with known hypersensitivity to it or in whom aspirin or NSAIDs precipitate attacks of asthma.</p>

<p>Aceclofenac is a non-steroidal drug with anti-inflammatory and analgesic properties. It is a potent inhibitor of the enzyme cyclooxygenase, which is involved in the production of prostaglandin. After oral administration, it is rapidly and completely absorbed an unchanged drug.</p>

<p>The use of Aceclofenac should be avoided in pregnancy and lactation unless the potential benefits to the other outweigh the possible risks to the fetus.</p>

<p>Caution should be exercised to patients with active or suspected peptic ulcer or gastro-intestinal bleeding moderate to severe hepatic impairment and cardiac or renal impairment. Caution should also be exercised in patients suffering from dizziness or urticaria.</p>

There are no clinical data on the use of Aceclofenac in children.

Drugs for Osteoarthritis, Drugs used for Rheumatoid Arthritis, Non-steroidal Anti-inflammatory Drugs (NSAIDs), Non-steroidal Anti-inflammatory Drugs (NSAIDs)

<p>keep in a dry place away from light and heat. Keep out of the reach of children.</p>